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The gut and physical digestionDate:
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Part 3 of 3

Along the gut

A sandwich you eat at lunch is in your mouth for less than a minute, in your stomach for a few hours and in your intestines for a day or more. The tube it travels through runs from the mouth to the anus. In this part you follow food along it, meet the organs that help on the way, and see two more kinds of physical digestion.

A model of the human body with the front of the abdomen taken off and lying beside it. Inside: the large brown liver at the top, with a small green gall bladder under it, the pink stomach beside the liver, the coiled small intestine in the middle and the wider large intestine around it. (enlarge)

The organs of the digestive system

Food passes along the alimentary canal, a tube from the mouth to the anus: the mouth, the oesophagus, the stomach, the small intestine and the large intestine. The small intestine has two parts: first the short duodenum, then the long ileum. The large intestine has parts too: the colon, then the rectum, which ends at the anus.

Four associated organs belong to the digestive system, but food never passes through them: the salivary glands, the pancreas, the liver and the gall bladder. They make or store juices that flow into the canal along small tubes called ducts, and the liver also deals with nutrients that the blood brings to it.

Outline of a human body from the mouth to the hips, with the digestive system labelled: mouth, salivary glands, oesophagus, stomach, liver, gall bladder, pancreas, duodenum, ileum, colon, rectum and anus. The alimentary canal runs from the mouth to the anus; the salivary glands, liver, gall bladder and pancreas lie beside it, joined to it by ducts. (enlarge)

Trap: "Food passes through the liver and the pancreas." Food stays inside the alimentary canal all the way. The pancreas sends its juice into the duodenum along a duct, and bile from the liver arrives the same way; food itself never enters them.

What each organ does

Five words name what happens to food:

  • Ingestion: the taking of substances, for example food and drink, into the body.
  • Digestion: the breakdown of food.
  • Absorption: the movement of nutrients from the intestines into the blood.
  • Assimilation: the uptake and use of nutrients by cells.
  • Egestion: the removal of undigested food from the body as faeces.
OrganWhat it does
MouthIngestion: food and drink enter here. The teeth chew food (physical digestion) and mix it with saliva.
Salivary glandsMake saliva, which wets food so it is easy to swallow; saliva contains an enzyme that starts digesting starch.
OesophagusCarries food from the mouth to the stomach, pushed along by the muscles in its wall.
StomachChurns food with its muscular wall (physical digestion) and mixes it with gastric juice, which contains an enzyme that starts digesting protein.
PancreasMakes pancreatic juice, which contains enzymes, and sends it into the duodenum.
LiverMakes bile. Its cells also take up nutrients from the blood and use or store them (assimilation): for example, they build amino acids into proteins and store glucose as glycogen.
Gall bladderStores bile and releases it into the duodenum.
DuodenumReceives pancreatic juice and bile; digestion continues.
IleumDigestion is completed, and the small, soluble molecules of digested food are absorbed into the blood (absorption), with much of the water.
ColonAbsorbs more water from the undigested food that is left.
RectumStores the faeces.
AnusEgestion: the faeces leave the body.

Assimilation happens in cells all over the body: a muscle cell that takes up glucose and uses it in respiration is assimilating it.

Key idea: Food passes along the alimentary canal: mouth, oesophagus, stomach, small intestine (duodenum, ileum) and large intestine (colon, rectum, anus). The salivary glands, pancreas, liver and gall bladder add juices or deal with nutrients. Food is ingested, digested, absorbed, assimilated, and what is not digested is egested.

Worked example

Following a piece of bread

Follow a piece of bread from the mouth to the anus. Name, in order, the parts of the alimentary canal it passes through, and the process at each main stage.

Mouth: ingestion; the teeth chew the bread and saliva starts digesting its starch. Oesophagus: carries it down to the stomach. Stomach: churns it and mixes it with gastric juice. Duodenum: pancreatic juice and bile are added and digestion continues. Ileum: digestion is completed, and the small, soluble molecules are absorbed into the blood. The blood carries them to cells, which take them up and use them: assimilation. Colon: more water is absorbed from what is left, such as the fibre. Rectum: the faeces are stored. Anus: egestion. The bread never passes through the salivary glands, the pancreas, the liver or the gall bladder: their juices come to it.

Worked example

Which process?

Name the process in each case: (a) a baby drinks milk; (b) glucose passes from the ileum into the blood; (c) a liver cell builds amino acids into a protein; (d) faeces leave the body.

(a) Ingestion: taking food and drink into the body. (b) Absorption: a nutrient moves from the intestine into the blood. (c) Assimilation: a cell takes up nutrients and uses them. (d) Egestion: undigested food leaves the body as faeces. Do not call (d) excretion: excretion removes waste made by the body's own cells, but faeces are mostly food that was never digested or absorbed, so it was never part of the body's cells.

The churning stomach

The stomach is a muscular bag. Its wall has thick layers of muscle, which contract and relax again and again for hours after a meal. This churns the food: it squeezes and turns it, breaks it into smaller pieces and mixes it with gastric juice, until it becomes a thick, creamy liquid. This is physical digestion, like the glass rod mashing the egg white: the food molecules are not changed. Smaller pieces have a larger surface area for the enzymes in the gastric juice, and later in the small intestine. A little at a time, the liquid then passes on into the duodenum.

Trap: "The stomach digests food only with its juice." The muscular wall of the stomach also digests food physically: churning breaks it into smaller pieces and mixes it with the juice.

Worked example

A stomach in a bag

A pupil puts some pieces of cracker and a little water into a sealed plastic bag and squeezes the bag with both hands, again and again, for two minutes. The crackers turn into a thick paste. Explain what the squeezing stands for, and why it helps digestion in the real stomach.

The squeezing hands stand for the muscles in the stomach wall, which contract and relax again and again: they churn the food. The crackers are broken into smaller pieces and mixed with the water, which stands for the gastric juice. This is physical digestion: the cracker is still cracker, with no chemical change. Smaller pieces have a larger surface area, so the enzymes can act on more of the food at once and digest it faster. The model leaves out the enzymes: it shows only the physical part.

Supplement: bile and fat droplets

Fats and oils do not mix with water. In the duodenum, fat from a meal would stay in large drops, and the enzyme that digests fat could work only at the surface of each drop. Bile changes that. It is made in the liver, stored in the gall bladder, and flows along the bile duct into the duodenum. Bile emulsifies fats and oils: it breaks large drops into many tiny droplets, which stay spread through the watery liquid. This is physical, not chemical: the fat molecules are not changed. But the tiny droplets have a much larger surface area, so the enzyme can digest the fat much faster.

Left: one large drop of oil in a watery liquid, with a few enzyme molecules on its surface. Right: after bile is added, the same volume of oil as a thousand droplets, each one tenth as wide, with enzyme molecules on all of them. A note says that the total surface area is ten times larger. (enlarge)

You can see an emulsion form in a test tube. Oil shaken with water alone soon floats back up as a separate layer. Shaken with water and a little bile, or with washing-up liquid, which emulsifies oil in the same way, it stays as a cloudy, creamy liquid of tiny droplets.

Two stoppered test tubes in a rack. Left: a clear yellow layer of oil floats on clear water. Right: the liquid is pale, cloudy and creamy all the way through, with no separate layer. (enlarge)

Key idea: (Supplement) Bile, made in the liver and stored in the gall bladder, emulsifies fats and oils in the duodenum: it breaks them into tiny droplets, with no chemical change. This increases their surface area for chemical digestion by enzymes.

Worked example

Without a gall bladder

Supplement. A patient has had their gall bladder removed. Their liver still makes bile, which now trickles slowly into the duodenum all the time. The doctor advises them to avoid large, fatty meals. Explain why.

Bile is made in the liver, so the patient still has some. But there is no gall bladder to store bile and release a large amount into the duodenum when a fatty meal arrives. After a large, fatty meal there is too little bile to emulsify all the fat, so much of it stays in large drops. Large drops have a small total surface area, so the enzyme that digests fat can reach only a little of it at a time, and the fat is digested slowly. A small meal with little fat needs less bile, so the bile that trickles in is enough.

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Scope and sources

Cambridge IGCSE Biology 0610 · 2026–2028 v3 · Original learning materials.

The organs of the digestive system and the associated organs (7.2.1) and the five processes of ingestion, digestion, absorption, assimilation and egestion (7.2.2); physical digestion and surface area (7.3.1, 7.3.2) through the egg-white practical; the types, structure and functions of human teeth (7.3.3–7.3.5); the churning stomach (7.3.6) and bile emulsifying fats (Supplement 7.3.7). Named digestive enzymes and their products are in the chemical digestion module, villi and absorption in a later module; tooth decay is not covered. Times in the experiment come from a teaching model.

Apparatus, amounts and times in the experiment are illustrative. Real practical work follows a teacher-approved safety method.

Official Cambridge syllabus